Amputation is a surgical procedure in which all or a portion of a limb is removed (ablated). Amputations are frequently done to prevent painful consequences, inevitable complications, or even a deadly conclusion. Diseases: 

• Lower limb arterial insufficiency: a narrowing or blockage of the major and medium-sized arteries. This indicates that insufficient blood and oxygen are getting to the limb’s extremities. High blood pressure, smoking, and diabetes are the main causes of this.
• Cancer or certain infections that impact the soft tissues and bones.

mishaps at work, home, or on the road, etc.